A “Green” Synthesis of N-(Quinoline-3-ylmethylene)benzohydrazide Derivatives and their Cytotoxicity Activities
نویسندگان
چکیده
Relatamos algumas moléculas híbridas baseadas na N-(quinolina-3-ilmetileno)benzoidrazida, cuja síntese foi realizada usando-se 2-cloroquinolina-3-carbaldeído e uma variedade de hidrazidas substituídas, em PEG 400. O solvente PEG 400 foi recuperado e reutilizado diversas vezes na presente reação, mostrando-se eficiente em termos de rendimento dos produtos. Alguns dos compostos sintetizados mostraram atividade citotóxica significativa quando testados in vitro.
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